Mika's Happy Medicine

Mika's Happy Medicine is a management simulation-style adventure game where you play as Mika, a futanari character who wields a mysterious drug called the "Drug of Happiness" to wreak havoc on the human world. The game focuses on corruption and mind control mechanics as you use the drug to manipulate human NPCs and transform society. While Mika is a futanari protagonist, the primary adult content centers on human characters rather than the futanari cast.